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In order to promote hand hygiene and help prevent cross-contamination between patients and staff, the CDC recommends glove use for all healthcare workers. It’s important to choose the right exam glove for your practice.

icon image of two gloves with blue outline

When choosing an exam glove, there are many factors to consider, including:

  • Your practice type
  • The types of procedures performed
  • Glove types available and their basic features

The type of glove to be used greatly depends on your practice type and the various procedures performed. Whether you’re performing frequent blood draws, seasonal flu tests, or yearly physical exams, the right glove can help protect patients and staff by reducing the risk of healthcare-associated infections (HAIs).

The list below represents various healthcare settings that would be likely to utilize exam gloves.

  • Physician Office/Specialty Clinic/Community Health Center
  • Phlebotomy
  • Laboratory
  • Long Term Care
  • Pharmacy/Oncology Clinic
  • Home Care
  • Urgent Care/Emergency Room
  • Environmental Services
Examination Gloves Indicated in
Clinical Situations
Direct Patient ExposureIndirect Patient Exposure
Potential for touching blood, body fluids, secretions, excretions and items visibly soiled by body fluids.– Contact with blood
– Contact with mucous membrane and with non-intact skin
– Potential presence of highly infectious and dangerous organism
– Epidemic or emergency situations
– IV insertion and removal; drawing blood
– Discontinuation of venous line
– Pelvic and vaginal examination
– Suctioning non-closed systems of endotracheal tubes
– Emptying emesis basins
– Handling/cleaning instruments
– Handling waste
– Cleaning up spills of body fluids
Gloves Not Indicated (except for CONTACT precautions)Direct Patient ExposureIndirect Patient Exposure
No potential for exposure to blood or body fluids, or contaminated environment.– Taking blood pressure, temperature and pulse
– Performing SC and IM injections
– Bathing and dressing the patient
– Transporting patient
– Caring for eyes and ears (without secretions)
– Any vascular line manipulation in absence of blood leakage
– Using the telephone
– Writing in the patient chart
– Giving oral medications
– Distributing or collecting patient dietary trays
– Removing and replacing linen for patient bed
– Placing non-invasive ventilation equipment and oxygen cannula
– Moving patient furniture

Now that you’ve considered your practice type and the procedures you perform, additional factors to consider while choosing the right glove include fit and comfort, elasticity and chemical resistance. The chart below offers basic recommendations based on glove type and common areas of concern.

Barrier protectionAllergen ContentStrength and durabilityelasticityfit and comfortchemical resistance
NitrileGood Choice 
Provides good barrier protection
Good Choice 
Contains no latex proteins
Can contain a low level of chemical allergens and curing agents
Good Choice 
Performs well with a modest tensile strength per the ASTM requirements
Good Choice 
Adequate flexibility
Does exhibit some memory and moldability
Good Choice 
Provides good comfort and fit due to increased memory and elasticity
Best Choice 
Provides good resistance to many chemicals
See chemical resistance chart
LatexBest Choice 
Provides good barrier protection
Not Recommended 
Contains protein and chemical allergens; check with specific manufacturer for allergen content
Best Choice 
Performs well with a modest tensile strength per the ASTM requirements
Best Choice 
High flexibility and memory
Best Choice 
Provides excellent comfort and fit due to its high elasticity
Retains its shape and fit during rigorous manipulation
Good Choice 
Provides good resistance to many chemicals
See chemical resistance chart
Vinyl
(Polyvinyl
Chloride)
Not Recommended 
May tear when put under significant stress, so protection is limited
Good Choice 
Contains no latex proteins
Can contain some curing agents and other chemical ingredients
Not Recommended 
Can break or puncture when put under tensile strain
Good Choice 
Exhibits some stretchability and memory
Not Recommended 
Limited elasticity
Fit and comfort can be limited
Wrist diameter can be large, making gloves baggy around the cuff after extended use
Not Recommended 
Easily permeated by organic solvents

In some healthcare settings, chemical resistance is one of the more important factors to consider when choosing an exam glove. The below chart offers an overview of chemicals that may be found in healthcare settings, along with their resistance ratings for nitrile and latex gloves.

ChemicalNitrile Resistance ratinglatex resistance rating
Acetaldehyde*  GoodGood
Ammonium HydroxideVery GoodVery Good
Citric Acid (10%)  Very GoodVery Good
CyclohexanolVery GoodFair
Ethyl Alcohol Very GoodVery Good
Ethyl Ether*GoodGood
FormaldehydeVery GoodVery Good
Formic Acid Very GoodVery Good
Hydrogen Peroxide (30%)GoodGood
Lactic Acid (85%) Very GoodVery Good
Oleic Acid Very GoodVery Good
Oxalic Acid Very GoodFair
Palmitic Acid Very GoodVery Good
PhenolFairFair
Potassium HydroxideVery GoodVery Good
Propyl Alcohol (Iso) Very GoodVery Good
Sodium Hydroxide Very GoodVery Good
Tannic AcidVery GoodVery Good
Triethanolamine (85%)Very GoodVery Good
 Xylene*FairPoor

Chemicals marked with an asterisk (*) are for limited use. This chart and its contents have been adapted from OSHA’s Chemical Resistance Selection Chart for Protective Gloves, and are not meant to be inclusive.Note: When selecting chemical-resistant gloves, be sure to consult the manufacturer’s recommendations, especially if the gloved hand(s) will be immersed in the chemical.