Molecular Reagent HemeScreen® ASXL1 For Research Use Only For HRM-enabled RT-PCR Machine / Cytopenia Panel 100 Tests

Features

• Precipio’s HemeScreen® offerings are Research Use Only (RUO) assays that screen for clinically actionable somatic mutations in targets of interest related to myeloproliferative disorders and haematological cancers
• The reagents are designed to be used in a clinical diagnostic laboratory by suitably trained personnel testing DNA extracted from whole blood or bone marrow using a PCR-based method and High Resolution Melt (HRM) Analysis
• ASXL1 (additional sex combslike 1) mutations can be seen in myelodysplastic syndrome (MDS), myeloproliferative neoplasms (MPN), chronic myelomonocytic leukemia (CMML), refractory cytopenia, persistent cytopenia with early detection of MDS and AML
• ASXL1 is often associated with RUNX1 cytogenetic abnormalities in both MDS and AML, as well as CEBPA in AML
• Free-Flow Reagent
• Each HemeScreen® reagent sets contains enough reactions for 100 samples in duplicate and includes enough Mutant control for 5 reactions
• Reagent sets should be stored in the dark between -18 °C and -25 °C in a constant temperature freezer until use
• Machine required HRM-enabled RT-PCR (example/ ThermoFisher Quantstudio 3 or higher)

More Information

• SDS