Molecular Reagent HemeScreen® IDH2 For Research Use Only For HRM-enabled RT-PCR Machine / AML Panel 100 Tests

Features

• Precipio’s HemeScreen® offerings are Research Use Only (RUO) assays thatscreen for clinically actionable somatic mutations in targets of interest related to myeloproliferative disorders and haematological cancers
• The reagents are designed to be used in a clinical diagnostic laboratory by suitably trained personnel testing DNA extracted from whole blood or bone marrow using a PCR-based method and High Resolution Melt (HRM) Analysis
• High Resolution Melting (HRM) is a screening technique, which allows the user to determine if the PCR fragment contains a variant or not based upon the dissociation of double-stranded DNA in the presence of an intercalating dye as the temperature increases
• IDH1 (isocitrate dehydrogenase 1) mutation is generally associated with decreased complete remission
• IDH1 mutation is often paired with NPM1 mutation and normal cytogenetics
• Free-Flow Reagent
• Each HemeScreen® reagent sets contains enough reactions for 100 samples in duplicate and includes enough Mutant control for 5 reactions
• Reagent sets should be stored in the dark between -18 °C and -25 °C in a constant temperature freezer until use

More Information

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