- Pharmaceuticals
Your single source for specialty drugs, generics and vaccines
Our large portfolio offers the convenience of getting your pharmaceuticals on the same order as your medical-surgical supplies and lab products.



Featured Products
Specialty Drugs
Generics Pharmaceuticals
Vaccines
McKesson Delivers
Delivering over 1/3 of the nation’s pharmaceuticals
Streamlined ordering and inventory management helps you consolidate ordering with access to over 10,000 pharmaceuticals, no minimum order requirements, expanded six month return policy on vaccines* and lowest unit of order available on most generics and vaccines.
Flexible and reliable delivery options provide next-day delivery to 95% of U.S. locations, a nationwide distribution network meeting all FDA requirements and dedicated delivery professionals who can deliver directly to office suites.
Dedicated customer support & account managers that offer fast, responsive support letting you focus on patient care.
Enroll in McKesson CSOSManager Today
Starting March 31, 2025, we will no longer accept paper 222 Forms for ordering CII controlled substances.
We’re excited to offer you a faster and more efficient way to manage your orders. Bid farewell to traditional paper 222 forms and step into the future with our online ordering solution. By enrolling in the Drug Enforcement Administration (DEA) Controlled Substance Ordering System (CSOS) by March 31, you can help ensure your service remains seamless and uninterrupted.
Follow These Steps:
1. Enroll in DEA CSOS
All new controlled substance customers must first obtain a CSOS certificate through the DEA. The enrollment process can be done entirely online through the DEA CSOS application portal. New accounts must sign up and complete a quick online identity verification to access the application portal and request a CSOS certificate. Please note, DEA processing times can take up to eight weeks, so please start soon to avoid interrupted service. For additional information regarding the DEA enrollment process, please visit the DEA CSOS Q&A page.
2. Install CSOS Certificate in McKesson SupplyManager
With your CSOS certificate in hand, the final step is to install it in SupplyManager and set up the CSOSManager platform. To do that, you can either use our step-by-step self-guided instructions document or you can schedule time with our CSOS Tech Support team to help assist with the installation.
Temporary Exceptions: We understand the transition may take some time, so temporary exceptions for using paper 222 Forms may be granted during your CSOS setup or during staff changes. These will be strictly limited to temporary disruptions.
To submit a request, please fill out our Exception Request Form.
Need Additional Support?
Drug Enforcement Administration CSOS Helpdesk / Support
(877) 332-3266 – wait times can be long
- Login or sign-up issues for the DEA Customer Application Portal
- Identity verification issues
- Status updates on CSOS certificate enrollment
McKesson Medical-Surgical CSOS Customer Support
- Temporary 222 Form exception requests and questions
- Questions or assistance with CSOS certificate enrollment through the DEA
McKesson Medical-Surgical CSOS Tech Support
(800) 422-0280 – Option 5 > Option 6
- CSOS certificate installation in McKesson SupplyManager
- Ordering or technical issues with our CSOS ordering platform, McKesson CSOSManager.
- Issues or assistance with CSOS certificate retrieval from the DEA (after receiving approval and activation notices)
McKesson CSOSManager FAQs
Controlled Substance Resources
The following resources may support an understanding of the regulatory landscape and the role McKesson is playing in the fight against controlled substance diversion and abuse.
Featured Services


Do you want to access our portfolio of over 10,000 pharmaceuticals?
If you are not currently purchasing pharmaceuticals from us, or have questions reach out to our dedicated account support.

*excludes flu vaccine
Please see full product inserts for prescribing information and refer to the Orange Book rating to confirm bioequivalency of generic equivalents.
Be advised that information contained herein is intended to serve as a useful reference for informational purposes only and is not complete clinical information. This information is intended for use only by competent healthcare professionals exercising judgment in providing care. McKesson cannot be held responsible for the continued currency of or for any errors or omissions in the information.
The product information contained in this document, including the product images and additional product materials, was collected from various supplier sources. All product claims and specifications are those of the product suppliers and have not been independently verified by McKesson Medical-Surgical or its affiliates (“McKesson”). McKesson is not responsible for errors or omissions in the product information. The properties of a product may change or be inaccurate following the posting or printing of the product information in the document, either in the print or online version. Caution should be exercised when using or purchasing any products from McKesson’s online or print documents by closely examining the product packaging and the labeling prior to use. Due to product changes, information listed in this document is subject to change without notice. This information is placed solely for your convenience in ordering and McKesson disclaims all responsibility for its completeness and accuracy, whether or not the inaccuracy or incompleteness is due to fault or error by McKesson.
©2024 McKesson Medical-Surgical Inc. All trademarks and registered trademarks are the property of their respective owners.